The Republic analyzes:

“Giffords will have to use all of her considerable campaign-trail talents to defend her votes for the stimulus package and the health-care and energy bills in a district that has a track record supporting ‘middle of the road’ candidates,” wrote analyst David Wasserman for the “Cook Political Report.”
Giffords, whose 8th Congressional District encompasses parts of Tucson and communities in Arizona’s southeastern corner, voted with the president 90 percent of the time last year, according to an analysis by the nonpartisan publication Congressional Quarterly.
Although Democratic Reps. Harry Mitchell and Ann Kirkpatrick also are considered vulnerable, they are less closely identified with Obama at a time when his priorities have been losing support in public-opinion polls and at the ballot box.

The paper notes at the end of the story that she has $1.6 million on hand.